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Rev. chil. obstet. ginecol ; 72(4): 210-216, 2007. tab
Article in Spanish | LILACS | ID: lil-477386

ABSTRACT

Antecedentes: La vitamina A, principalmente en su forma de ácido todo trans-retinoico, desempeña una función de vital importancia durante el desarrollo gestacional en todos los tejidos y órganos del cuerpo. Objetivo: Determinar los niveles de ácido retinoico en el suero de sangre de cordón umbilical y relacionarlos con el peso/edad gestacional del recién nacido y el consumo materno de vitamina A, conjuntamente con variables socio-económicas y nutricionales. Método: Estudio descriptivo de corte transversal, analizando un total de 62 neonatos y sus madres, provenientes de las maternidades de los Hospitales San José y Barros Luco-Trudeau, Santiago de Chile. Resultados: En la población en estudio se observó una relación directa entre el peso/edad gestacional del neonato y el consumo materno de vitamina A, pero no con los niveles de esa vitamina en el suero de sangre de cordón umbilical. Se encontró que el consumo medio de vitamina A en las embarazadas fue sólo de 2298 +/- 1416,8 Ul, siendo la dosis recomendada por OMS de 8000 Ul. Conclusión: Existe asociación entre la ingesta de vitamina A y el estado nutricional materno en relación con el peso/edad gestacional del neonato. Debido a que los requerimientos nutricionales del feto están privilegiados por sobre los maternos, no se observaron diferencias en las características antropométricas del neonato asociadas a la ingesta materna de vitamina A.


Background: Vitamin A, mainly in their form of retinoic acid, it carries out a function of vital importance during the gestational development, in all the tissues and organs of the body. Objective: To evaluate the levels of retinoic acid in the serum of blood from umbilical cord and to relate them with the weight/gestational age ratio of the newborns and the maternal intake of vitamin A, jointly with socioeconomic and nutritional variables. Method: A descriptive study of traverse court, in the maternities of the Hospitals San José and Barros Luco-Trudeau of Santiago, Chile, studying a total of 62 cases. Results: In the population in study a direct relationship was observed between the newborn ratio weight/gestational age and the maternal consumption of vitamin A, but no relationship was found among the same weight/gestational age ratio and the levels of this vitamin in the serum of blood of umbilical cord. On the other hand, it was found that the average consumption of vitamin A in the maternities it was of 2298 +/- 1416.8 IU, being the dose recommended by WHO for pregnant of 8000 IU, therefore, the whole population in study had a faulty consumption of vitamin A. Conclusion: Exists association among the intake of vitamin A and the maternal nutritional state with the weight/gestational age ratio of the newborn and the concentration of trans-retinoic acid in the umbilical cord. Because the nutritional requirements of the fetus are privileged over the maternal ones, differences were not observed in the newborn anthropometries features associated to the maternal vitamin A intake.


Subject(s)
Humans , Female , Infant, Newborn , Adult , Fetal Development/physiology , Fetal Blood , Maternal Nutritional Physiological Phenomena/physiology , Prenatal Nutritional Physiological Phenomena/physiology , Tretinoin/blood , Analysis of Variance , Anthropometry , Birth Weight , Cross-Sectional Studies , Epidemiology, Descriptive , Gestational Age , Nutritional Status , Socioeconomic Factors , Vitamin A/physiology
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